What are the Mechanisms Regulating E-Cadherin Expression?
E-Cadherin expression is regulated at multiple levels, including transcriptional, post-transcriptional, and post-translational mechanisms. Transcription factors such as Snail, Slug, and Twist are known to repress E-Cadherin transcription during EMT. MicroRNAs and various signaling pathways, like the Wnt/β-catenin pathway, also play roles in modulating E-Cadherin levels.
