What are the Mechanisms for Repairing Double Strand Breaks?
Cells have two main pathways to repair DSBs: homologous recombination (HR) and non-homologous end joining (NHEJ). HR is an error-free repair process that uses a sister chromatid as a template, making it most active during the late S and G2 phases of the cell cycle. NHEJ, on the other hand, is a quicker but error-prone repair mechanism that ligates the broken ends together and operates throughout the cell cycle.
