What are the Limitations of Using CD31 as a Marker?
While CD31 is a reliable marker for endothelial cells, it is not entirely specific. CD31 expression is also found on platelets and certain leukocytes, which can lead to potential misinterpretation in some contexts. Therefore, it is often used in conjunction with other endothelial markers, such as von Willebrand factor or VE-cadherin, to improve accuracy in identifying endothelial cells.
