How are Matrix Vesicles Involved in Pathological Conditions?
Matrix vesicles are not only involved in normal biomineralization but also play a role in pathological conditions. For example, in diseases such as osteoarthritis and vascular calcification, the dysregulation of matrix vesicle formation and function can lead to abnormal mineral deposition. This can result in the hardening and loss of function of tissues that are normally non-mineralized.
