What are the Implications of Chronic Microglial Activation?
While acute microglial activation is generally beneficial for resolving infections and repairing tissue, chronic activation can be detrimental. Sustained microglial activation is often linked to chronic neuroinflammation, which can exacerbate neurodegenerative processes and lead to further neuronal damage. This underscores the need for therapeutic strategies that can modulate microglial activation to prevent or mitigate chronic inflammation.
