What are the Molecular Mechanisms Behind Cytoskeletal Breakdown?
Cytoskeletal breakdown involves the action of various proteases and regulatory proteins. For example, caspases, a family of proteases, play a significant role in apoptosis by cleaving cytoskeletal proteins. Phosphorylation and dephosphorylation events also regulate the stability of cytoskeletal components. Additionally, calcium ions can activate specific enzymes that degrade cytoskeletal filaments.