clathrin mediated endocytosis

What Are the Key Proteins Involved?

Several key proteins are involved in CME:
1. Clathrin: Forms the triskelion structure that assembles into the lattice coating the vesicle.
2. Adaptor Proteins (AP2): Recognize cargo and recruit clathrin to the membrane.
3. Dynamin: A GTPase responsible for severing the vesicle from the plasma membrane.
4. Auxilin and Hsc70: Facilitate the uncoating of clathrin from the vesicle.

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