What are the Implications of Tissue Heterogeneity in Pathology?
Tissue heterogeneity has significant implications in pathology: 1. Cancer: Tumor heterogeneity can result in varied responses to treatments and the emergence of drug resistance. Understanding the heterogeneity within a tumor can aid in the development of more effective therapeutic strategies. 2. Inflammatory Diseases: Heterogeneity in immune cell populations can influence the progression and resolution of inflammatory conditions. 3. Fibrosis: Variations in fibroblast activity and ECM composition can lead to different patterns of tissue scarring and fibrosis.
