Tissue heterogeneity can be classified based on several factors: 1. Cellular Composition: Variations in the types and proportions of cells, such as epithelial, connective, muscle, or nervous cells. 2. Extracellular Matrix (ECM): Differences in the composition and organization of the ECM, which provides structural support and biochemical signals to cells. 3. Functional Properties: Disparities in the metabolic, mechanical, and signaling functions of cells within a tissue.
