Hypoxia plays a significant role in various diseases, particularly in cancer, where it contributes to tumor progression and resistance to therapy. Hypoxic conditions within tumors can lead to the activation of pathways that promote cell survival, angiogenesis, and metastasis. In cardiovascular diseases, hypoxia due to reduced blood flow can lead to tissue damage and heart failure. Understanding the histological changes induced by hypoxia is crucial for developing targeted therapies.
