What are the Implications of FOXO1 Dysregulation in Diseases?
Dysregulation of FOXO1 has been implicated in various diseases. In cancer, aberrant FOXO1 activity can lead to uncontrolled cell proliferation and resistance to apoptosis. In metabolic disorders like diabetes, altered FOXO1 activity can result in impaired glucose homeostasis. Understanding the role of FOXO1 in these conditions can provide insights into potential therapeutic targets.