What are the Cellular Effects of Genotoxic Agents?
The cellular effects of genotoxic agents can be profound. They can cause DNA adducts, strand breaks, and chromosomal rearrangements. In histological studies, these effects are often visible as structural changes in the chromatin, nuclear fragmentation, and the presence of micronuclei. Prolonged exposure to genotoxic agents can lead to apoptosis or uncontrolled cell proliferation, contributing to cancer development.
