What are the Implications of Apoptosis Inhibition in Cancer?
In cancer, the inhibition of apoptosis allows malignant cells to evade cell death, contributing to tumor growth and resistance to therapy. Many cancers exhibit overexpression of anti-apoptotic proteins like Bcl-2 or downregulation of pro-apoptotic proteins like Bax. Targeting these molecules with specific therapeutics is a promising strategy for cancer treatment, aiming to restore the apoptotic pathways and induce cell death in cancer cells.
