What are the Histological Features of Atherosclerosis?
Atherosclerosis is a key focus in vascular histology due to its prevalence and severe consequences. Histological features include:
- Intimal Thickening: The innermost layer of the artery wall becomes thickened due to the accumulation of lipid-laden macrophages (foam cells). - Fibrous Cap Formation: A layer of fibrous tissue forms over the lipid core, which can rupture and lead to thrombosis. - Calcification: Deposits of calcium can form within the plaques, making the arteries stiffer and more prone to rupture.
