What are the histological changes observed with ARB therapy?
Histological studies have shown that ARB therapy can lead to significant changes in tissue structure. These include reduced inflammation, decreased fibrosis, and improved vascular remodeling. In the kidneys, ARBs can help to reduce glomerulosclerosis and tubulointerstitial fibrosis, while in the heart, they may prevent or reverse the hypertrophic changes associated with chronic hypertension.