What is the Role of Staining in Identifying Pathological Changes?
Staining is crucial for identifying pathological changes in tissues. Different stains are used to differentiate between various tissue components. For instance, H&E staining is commonly used for general tissue structure, while special stains like Periodic Acid-Schiff (PAS) can highlight glycogen and other polysaccharides. Immunohistochemistry (IHC) can be used to detect specific antigens in tissues, providing detailed information about cellular function and pathology.