Angiotensin II has several adverse effects on cardiac tissue, including promoting [cardiac hypertrophy](https://) and fibrosis. These changes can lead to heart failure and other cardiovascular diseases. ARBs mitigate these effects by blocking the action of angiotensin II, thereby reducing cellular hypertrophy and fibrotic changes in the cardiac tissue. This cardioprotective effect helps in improving the overall [cardiac function](https://) and reducing the risk of heart failure.
