At the cellular level, ARBs function by binding to the angiotensin II type 1 (AT1) receptor, thereby preventing angiotensin II from exerting its effects. This inhibition leads to the dilation of blood vessels and a reduction in the release of aldosterone, a hormone that promotes sodium retention and potassium excretion. The inhibition of these pathways helps in the management of hypertension and other cardiovascular disorders.
