- Barrier Formation: It physically isolates the damaged area from the surrounding healthy tissue, preventing the spread of potentially harmful molecules. - Regulation of Inflammation: The glial scar modulates the inflammatory response, balancing the need for clearance of debris and the prevention of excessive inflammation. - Tissue Repair and Regeneration: While the glial scar can inhibit axonal regeneration, it also provides a scaffold for the migration of new cells and the repair of the damaged area.