What are the Common Histological Findings Associated with Bilirubin?
In histological samples, bilirubin deposition can lead to several characteristic findings: - Jaundice: Yellow discoloration of tissues, especially in the sclera and skin. - Cholestasis: Accumulation of bile pigments in hepatocytes and bile ducts. - Bile Plugs: Obstruction of bile flow leading to bile plugs in bile canaliculi. - Hepatocellular Damage: Necrosis or apoptosis of hepatocytes, often accompanied by inflammation and fibrosis.
