How is Bilirubin Detected in Histological Samples?
Bilirubin can be detected in histological samples using special staining techniques. One common method is the Fouchet's stain, which highlights bilirubin as a greenish color. Immunohistochemistry can also be employed to detect the presence of bilirubin-associated proteins and enzymes. Advanced techniques like mass spectrometry imaging are also used for more precise localization and quantification.