What Role Do Genetic Interactions Play in Tissue Homeostasis?
In adult tissues, genetic interactions are essential for maintaining homeostasis and function. Stem cells and progenitor cells rely on a network of genetic interactions to balance cell proliferation and differentiation. For example, in the intestinal epithelium, the Wnt signaling pathway interacts with other genetic pathways to regulate the continuous renewal of the tissue. Mutations or dysregulation in these interactions can result in diseases such as cancer or degenerative conditions.
