How is Pleomorphism Assessed in Histological Samples?
Pleomorphism is assessed by examining tissue samples under a microscope. Pathologists look for variations in cell and nuclear morphology across the tissue. Special staining techniques, such as Hematoxylin and Eosin (H&E) staining, are commonly used to highlight cellular and nuclear details. The degree of pleomorphism is then categorized, often using grading systems specific to different types of cancers.