What is the Role of Muscle Biopsy in Diagnosing Myopathies?
A muscle biopsy is a critical diagnostic tool for myopathies, providing direct insight into muscle tissue structure and pathology. The biopsy involves the removal of a small sample of muscle tissue, which is then processed and examined under a microscope. Various staining techniques, such as Hematoxylin and Eosin (H&E), Gomori trichrome, and immunohistochemical staining, are employed to highlight different cellular components and abnormalities.
