What are the Clinical Implications of Cell Cycle Arrest?
Understanding cell cycle arrest has several clinical implications:
Cancer therapy: Many cancer treatments aim to induce cell cycle arrest in rapidly dividing tumor cells, allowing for targeted destruction of malignant cells while sparing normal tissue. Neurodegenerative diseases: Cell cycle arrest mechanisms can play a role in the progression of diseases like Alzheimer's and Parkinson's, where neuronal cell death occurs. Aging: As cells age, their ability to properly regulate the cell cycle diminishes, leading to increased susceptibility to diseases and cellular dysfunction.