DNA damage: Exposure to radiation, chemicals, or other factors can damage DNA, prompting the cell to halt the cycle and initiate repair mechanisms. Nutrient deprivation: A lack of essential nutrients can signal the cell to stop dividing until conditions improve. Oxidative stress: High levels of reactive oxygen species (ROS) can damage cellular components, leading to cell cycle arrest. Tumor suppressors: Proteins like p53 can induce cell cycle arrest in response to various stress signals to prevent the propagation of damaged cells.
