NSE has several important clinical applications: 1. Diagnosis of Neural and Neuroendocrine Tumors: NSE is a valuable marker for identifying tumors of neural origin, such as neuroblastoma and small cell lung carcinoma. 2. Prognosis and Monitoring: Elevated serum NSE levels can be indicative of disease progression or recurrence in patients with neuroendocrine tumors. Monitoring NSE levels can help assess the effectiveness of treatment. 3. Differentiation of Tumor Types: NSE staining can help differentiate between tumors of neural origin and other types of tumors, aiding in accurate diagnosis and appropriate treatment planning.
