γH2AX has several clinical applications, particularly in cancer research and treatment. It is used to monitor the effectiveness of radiotherapy and chemotherapy by quantifying DNA damage in tumor cells. Elevated levels of γH2AX in patient samples can also serve as a prognostic marker, indicating poor prognosis due to increased genomic instability. Furthermore, γH2AX is utilized in drug development to screen for potential genotoxicity of new compounds.
