Histopathological analysis provides detailed information about the architecture and cellular composition of the prostate tissue. Key features assessed include:
- Cellular Morphology: Cancerous cells often exhibit abnormal shapes, sizes, and arrangements compared to normal prostate cells. - Acinar Structures: The presence of irregular and distorted acinar structures is indicative of malignancy. - Perineural Invasion: The invasion of cancer cells into the nerves surrounding the prostate is a sign of advanced disease. - Gleason Patterns: The Gleason grading system classifies prostate cancer based on the patterns of glandular differentiation and helps in predicting the prognosis.
