Can γH2AX be Used in Combination with Other Biomarkers?
Yes, γH2AX is frequently used in combination with other biomarkers to enhance the accuracy of DNA damage assessment. For instance, co-staining with markers such as 53BP1 or RAD51 can provide insights into the specific DNA repair pathways activated in response to damage. Additionally, combining γH2AX with cell cycle markers can help determine the phase of the cell cycle during which the damage occurred, providing further context to the findings.