What Happens When Signaling Pathways are Dysregulated?
Dysregulation of signaling pathways can lead to various diseases, including cancer, diabetes, and neurodegenerative disorders. For example, aberrant signaling through the PI3K/AKT pathway is a common feature in many cancers, leading to uncontrolled cell growth and survival. Similarly, mutations in components of the TGF-β pathway can result in fibrotic diseases and cancer.
