What Are the Challenges in Integrating Multi-Omics Data with Histology?
Integrating multi-omics data with histology is fraught with challenges:
1. Data Complexity: Multi-omics datasets are often large and complex, requiring sophisticated computational tools for integration and analysis. 2. Data Standardization: Different omics platforms may have varying data formats and quality, complicating the integration process. 3. Spatial Resolution: Linking molecular data to specific histological features requires high spatial resolution, which can be technically challenging. 4. Interdisciplinary Collaboration: Effective integration often necessitates collaboration between histologists, molecular biologists, bioinformaticians, and data scientists.