What Signaling Pathways Influence Lineage Commitment?
Various signaling pathways influence the commitment of progenitor cells to a specific lineage. The Wnt, Notch, and Hedgehog pathways are well-known for their roles in cell differentiation. These pathways interact with specific transcription factors to regulate the expression of genes that drive lineage commitment. Understanding these signals is essential for manipulating progenitor cells in regenerative medicine.