What Technologies Are Used in Multi-Omics Histology?
Several advanced technologies facilitate the integration of multi-omics data in histology:
1. Laser Capture Microdissection (LCM): Allows for the precise extraction of specific cells or tissue regions from histological sections, which can then be subjected to various omics analyses. 2. Mass Spectrometry Imaging (MSI): Enables the spatial mapping of metabolites and proteins within tissue sections. 3. Single-cell RNA Sequencing (scRNA-seq): Provides transcriptomic profiles at the single-cell level, aiding in the understanding of cellular diversity within tissues. 4. Spatial Transcriptomics: Combines RNA sequencing with positional information within tissue sections to map gene expression spatially.
