What Are the Challenges in Heart Regeneration Research?
Despite significant progress, several challenges remain in the field of heart regeneration. One major challenge is the limited regenerative capacity of adult human hearts. Additionally, understanding the exact signaling pathways and molecular mechanisms that regulate heart regeneration is crucial but complex. There are also concerns regarding the integration and functionality of newly formed tissue, as well as potential risks associated with stem cell therapies, such as tumorigenesis and immune rejection.