What are the Applications of Probe Hybridization in Histology?
Probe hybridization has a wide range of applications in histology: - Detection of Pathogens: It can be used to detect bacterial, viral, or fungal DNA/RNA within tissue samples, aiding in the diagnosis of infections. - Gene Expression Analysis: By using RNA probes, researchers can study the expression patterns of specific genes within different tissues or under various conditions. - Identification of Genetic Disorders: DNA probes can detect chromosomal abnormalities, such as deletions, duplications, and translocations, which are associated with various genetic disorders. - Cancer Research: Probe hybridization techniques can identify specific genetic mutations or gene expression changes associated with different types of cancer, aiding in diagnosis and treatment planning.
