How Do Progesterone Receptors Interact with Other Hormonal Pathways?
Progesterone receptors do not act in isolation; they interact with other hormonal pathways, including those regulated by estrogen, androgens, and glucocorticoids. These interactions can be synergistic or antagonistic, influencing a wide range of physiological processes. For example, estrogen upregulates PR expression, thereby enhancing the tissue's sensitivity to progesterone.