myelodysplastic syndromes

How is MDS Classified?

The World Health Organization (WHO) classification system divides MDS into several subtypes based on specific morphological and cytogenetic features:

MDS with Single Lineage Dysplasia (MDS-SLD): Dysplasia in one myeloid cell line with fewer than 5% blasts in bone marrow.
MDS with Multilineage Dysplasia (MDS-MLD): Dysplasia in two or more myeloid cell lines.
MDS with Ringed Sideroblasts (MDS-RS): Defined by the presence of ringed sideroblasts and varying degrees of dysplasia.
MDS with Excess Blasts (MDS-EB): Characterized by a higher percentage of blasts, further subdivided into MDS-EB1 and MDS-EB2 based on blast count.

Frequently asked queries:

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