FISH has a wide range of applications in histology, including:
Cancer Diagnosis: FISH is used to identify genetic abnormalities in cancer cells, such as gene amplifications, deletions, and translocations. This information is crucial for diagnosis, prognosis, and treatment planning. Prenatal Diagnosis: FISH is used in prenatal testing to detect chromosomal abnormalities, such as Down syndrome, in fetal cells obtained from amniocentesis or chorionic villus sampling. Infectious Disease: FISH can be used to detect specific pathogens in tissue samples, aiding in the diagnosis of infectious diseases. Genetic Research: FISH is a valuable tool for studying the organization and behavior of chromosomes in various tissues, contributing to our understanding of genetic diseases and developmental biology.
