In histological samples, lipid laden macrophages are typically identified using various staining techniques. Hematoxylin and eosin (H&E) staining can reveal their foamy appearance due to the lipid content. However, more specific staining methods such as Oil Red O and Sudan IV, which are lipid-specific stains, can be employed for more precise identification. Immunohistochemistry (IHC) can also be used to detect specific markers like CD68, which is commonly expressed on macrophages.
