t-SNAREs, or target SNAP receptors, are a family of proteins located on the membranes of target compartments within a cell. They play a critical role in the process of vesicle fusion, which is essential for intracellular transport, neurotransmission, and the secretion of various molecules. By facilitating the docking and fusion of vesicles, t-SNAREs ensure that cargo is accurately delivered to specific cellular destinations.