The function of t-SNAREs in vesicle fusion is highly coordinated and involves several key steps. First, t-SNAREs interact with their complementary v-SNAREs (vesicle SNAP receptors) present on the vesicle membrane. This interaction forms a stable SNARE complex, which brings the vesicle and target membranes into close proximity. The subsequent fusion of these membranes enables the transfer of cargo from the vesicle into the target compartment.
