What Are Some Histological Features of Carcinogenesis?
Histological examination of tissues can reveal several features indicative of carcinogenesis. These include increased cellular proliferation, abnormal mitotic figures, loss of differentiation, and changes in tissue architecture. For instance, the presence of dysplasia indicates abnormal cell growth and differentiation, often considered a precursor to cancer. Invasive cancer can be identified by the ability of cancer cells to breach the basement membrane and infiltrate surrounding tissues. Additionally, histological analysis can reveal the presence of necrosis, angiogenesis, and inflammatory infiltrates, all of which are associated with tumor progression.
