Several protein biomarkers are widely used in histology:
HER2: Overexpressed in some breast cancers, indicating aggressive disease but also responsiveness to targeted therapies like trastuzumab. PSA: Prostate-specific antigen, used primarily in the diagnosis and monitoring of prostate cancer. CA-125: A marker for ovarian cancer, useful in diagnosis and monitoring of treatment response. CD20: Found on B-cells, it is targeted in certain types of lymphoma treatments. Ki-67: A proliferation marker used to assess the growth fraction of a given cell population, commonly used in cancer studies.
