Serotonergic receptors are a group of G-protein-coupled receptors and ligand-gated ion channels located on the cell surface that bind serotonin. These receptors are divided into several classes, such as 5-HT1, 5-HT2, 5-HT3, 5-HT4, and so on. Each class has subtypes, and they are involved in different physiological processes. For example, 5-HT3 receptors are ion channels primarily involved in the gastrointestinal tract and play a role in nausea and vomiting.