Retinoic Acid Receptors (RARs) are a group of nuclear receptors that mediate the biological effects of retinoic acid, the active metabolite of vitamin A. These receptors play crucial roles in regulating gene expression, influencing cell differentiation, proliferation, and apoptosis. The RARs are composed of three main isoforms: RAR-α, RAR-β, and RAR-γ, each encoded by distinct genes and exhibiting specific tissue distribution and functions.
