nod like receptors (nlrs)

What are NLRs?

NLRs are a group of proteins located in the cytoplasm of cells. They are part of the larger family of Pattern Recognition Receptors (PRRs), which detect harmful substances. Structurally, NLRs share a common domain architecture, including a leucine-rich repeat (LRR) domain for ligand recognition, a nucleotide-binding oligomerization domain (NACHT) for oligomerization, and an effector domain, which often includes a caspase recruitment domain (CARD) or a pyrin domain (PYD).

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