What are Guanine Nucleotide Dissociation Inhibitors (GDIs)?
Guanine Nucleotide Dissociation Inhibitors (GDIs) are regulatory proteins that play a crucial role in the function of small GTPases, a family of proteins involved in various cellular processes such as cell growth, cytoskeletal organization, and intracellular trafficking. GDIs regulate the activity of these GTPases by inhibiting the release of GDP, thereby preventing the binding of GTP and keeping the GTPase in its inactive state.
