Lack of maintenance can lead to several issues, including:
Equipment Failure: Instruments such as microtomes, staining machines, and microscopes require regular calibration and upkeep. Failure to maintain these can result in inaccurate cuts, poor staining, and suboptimal imaging. Contamination: Unmaintained equipment and workspaces can become breeding grounds for contaminants, leading to erroneous results. This is especially critical in immunohistochemistry where contamination can affect antibody binding and subsequent analysis. Decreased Reproducibility: Consistency is key in histology. Lack of maintenance can introduce variables that compromise the reproducibility of results, making it difficult to compare findings across different laboratories or studies.