To enhance clarity in histological samples, consider the following tips: 1. Optimize Fixation: Ensure proper fixation time and use appropriate fixatives to preserve tissue integrity. 2. Careful Sectioning: Use a well-maintained microtome and ensure sections are of consistent and appropriate thickness. 3. Proper Staining: Follow standardized staining protocols and adjust staining times to achieve optimal contrast. 4. Quality Control: Regularly check and maintain equipment, and use high-quality reagents and consumables.